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Masteron (drostanolone propionate) is a moderately anabolic steroid that promotes increases in hardness, lean body mass and strength which has a positive effect on the potential for fat loss.Another compound is the hormone epidermal growth factor analog, epidermal growth factor receptor. These two hormones, when combined, act as an increase in epidermal cell growth, which increases both hydrolase enzyme activity and increases surface area of the cells.Propionate, but not butanediol acetate can reduce blood cholesterol (as does resveratrol), the main factor in the formation of HDL cholesterol in blood.Many studies suggest that propionate has an anti-aging effect: reducing free radicals in rats and improving cognitive (brain), muscular (muscle), and cardiovascular (heart) function; there does not appear to be any negative impact on bone density. It also seems to reduce bone loss in some elderly people who have osteoporosis (in some studies it can reverse the osteoporosis). It has been shown to decrease the number of beta-amyloid (anti-apoptotic) proteins relative to cholesterol in animal studies, and in rats it has been shown to inhibit the formation of beta-amyloid plaques and decrease the severity of the Alzheimer's disease.It has been associated with reductions in brain, heart, and muscle loss with aging, and appears to also have anti-aging effects, reducing brain and muscle loss with aging4 Interactions with Hormones4.1. TestosteronePropionate has been shown in preclinical models to have a positive effects on the ratio of testosterone to cortisol. Propionate appears to induce a more efficient conversion of testosterone to cortisol. This effect appears to also occur in humans. It is thought that this occurs because propionate has some of the same biological properties as testosterone; it helps reduce the blood volume by decreasing water content in tissues and increasing a fatty acid called oleic acid.Propionate also appears to stimulate skeletal muscle mass.One study has shown that propionate may be synergistic with resveratrol's benefits against muscle loss. However, it did not appear synergistic with resveratrol's anti-aging abilityPropionate appears to have a protective effect against the oxidative stress associated with aging, as it increases glutathione levels and prevents the development of oxidative stress.The anti-oxidantRelated Article: